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J Infect Dis ; 223(3): 381-388, 2021 02 13.
Article in English | MEDLINE | ID: covidwho-1082797

ABSTRACT

BACKGROUND: Care homes have experienced a high number of coronavirus disease 2019 (COVID-19)-related deaths among residents since the onset of the pandemic. However, up to May 2020, there has been a lack of information about the extent of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among residents and staff in care homes and limited testing in this setting. METHODS: Combined nose and throat swab testing for SARS-CoV-2 RNA was carried out in 2455 residents and staff across 37 care homes in the London Borough of Bromley across a 3-week period. Results were reported within 24 hours of sample delivery, and data were collected on the presence or absence of symptoms. RESULTS: Overall, the point prevalence of SARS-CoV-2 infection was 6.5%, with a higher rate in residents (9.0%) than in staff (4.7%). A key finding was the high proportion of asymptomatic infection detected in staff (69%) and residents (51%), with evidence of underdetection of symptoms by care home staff. CONCLUSIONS: The high proportion of asymptomatic infection combined with underdetection of symptoms by care home staff indicates that offering a test to all residents and staff in care homes with rapid reporting of results would assist accurate identification of infected individuals, facilitating prompt infection prevention and control action.


Subject(s)
COVID-19/virology , Homes for the Aged/statistics & numerical data , RNA, Viral/genetics , SARS-CoV-2/genetics , Adolescent , Adult , Aged , Aged, 80 and over , Asymptomatic Infections/epidemiology , COVID-19/diagnosis , COVID-19/epidemiology , COVID-19 Testing/methods , Female , Humans , London/epidemiology , Male , Middle Aged , Pandemics , Prevalence , RNA, Viral/isolation & purification , SARS-CoV-2/isolation & purification , Young Adult
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